Netherland Diethyl(Phenylacetyl)Malonate CAS 20320-59-6

 


In the rapidly evolving world of pharmaceuticals, agrochemicals, and organic synthesis, the significance of specialized chemical compounds cannot be overstated. Among these, Netherland Diethyl(Phenylacetyl)Malonate with CAS number 20320-59-6 stands out due to its unique chemical properties and versatile applications. This compound plays a crucial role in the synthesis of complex molecules, pharmaceutical intermediates, and agrochemical agents.

If you're a chemist, researcher, or industry professional seeking in-depth insights into this chemical, you're in the right place. This comprehensive guide will explore everything from its chemical structure and properties to its applications, safety considerations, and sourcing options.

What is Netherland Diethyl(Phenylacetyl)Malonate?

Netherland Diethyl(Phenylacetyl)Malonate is a specialized organic compound classified within the malonate ester family. Its systematic chemical name is Diethyl (phenylacetyl)malonate, and it bears the CAS registry number 20320-59-6. The compound is characterized by its ester functionalities and phenylacetyl groups, which confer specific reactivity profiles advantageous in organic synthesis.

Chemical Structure and Formula

  • Molecular Formula: C18H19O5
  • Molecular Weight: Approximately 330.35 g/mol
  • Structural Features: The molecule consists of a malonate backbone esterified with diethyl groups and substituted with a phenylacetyl moiety.

Understanding its chemical structure is essential for grasping its reactivity and potential applications.

Synthesis and Production

The synthesis of Netherland Diethyl(Phenylacetyl)Malonate typically involves multi-step organic reactions, often starting from commercially available precursors such as phenylacetic acid derivatives and malonate esters. The process includes esterification, acylation, and subsequent purification steps to obtain high purity.

Key Production Methods

  • Esterification of malonic acid derivatives: Utilizing alcohols and acid catalysts.
  • Acylation of malonate esters: Introducing phenylacetyl groups via acyl chlorides or anhydrides.
  • Purification processes: Recrystallization, chromatography, and distillation to ensure compound purity.

Leading chemical manufacturing companies in the Netherlands and globally produce this compound under stringent quality controls, adhering to industry standards.

Applications of Netherland Diethyl(Phenylacetyl)Malonate

The versatility of this compound makes it valuable across multiple industries. Below are some of its primary applications:

1. Pharmaceutical Industry

  • Intermediate in Drug Synthesis: Used as a building block in synthesizing complex pharmaceuticals, especially in the development of antiviral, anticancer, and neuroactive agents.
  • Chiral Synthesis: Facilitates the production of chiral molecules due to its stereochemical properties.

2. Organic Synthesis and Research

  • Precursor in Organic Reactions: Acts as a key intermediate in various organic reactions, including alkylation and cyclization.
  • Synthesis of Heterocyclic Compounds: Used in the preparation of heterocycles, which are essential in medicinal chemistry.

3. Agrochemical Development

  • Pesticide Intermediates: Serves as a precursor in the synthesis of certain pesticides and herbicides.

4. Material Science

  • Polymer Precursors: Potential use in developing specialty polymers due to its functional groups.

5. Specialty Chemicals

  • Chemical Research and Development: A vital reagent for academic and industrial research focusing on novel chemical entities.

Safety and Handling

Like many chemical compounds, proper safety protocols are critical when handling Netherland Diethyl(Phenylacetyl)Malonate:

  • Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
  • Personal Protective Equipment (PPE): Use gloves, goggles, and lab coats.
  • Exposure: Minimize inhalation, ingestion, and skin contact.
  • Disposal: Follow local environmental regulations for chemical waste disposal.

Consult the Material Safety Data Sheet (MSDS) for detailed safety information.

Regulatory Status and Compliance

The chemical is registered and regulated under various international standards depending on its intended use. Manufacturers and users must comply with:

  • REACH Regulation (EU)
  • TSCA (USA)
  • Other regional safety and environmental standards

Ensuring compliance guarantees safe handling, transportation, and usage.

Sourcing and Purchasing

For industries and researchers interested in sourcing Netherland Diethyl(Phenylacetyl)Malonate (CAS 20320-59-6), reputable chemical suppliers and manufacturers should be contacted.

Why Choose Reliable Suppliers?

  • High Purity Standards: Ensures consistency in research and production.
  • Certifications: ISO, GMP, and other regulatory compliances.
  • Technical Support: Assistance in handling, storage, and application.

Leading Suppliers

  • BMK Oil (as referenced in the site bmk-oil.com)
  • Sigma-Aldrich
  • TCI Chemicals
  • Alfa Aesar

Always verify supplier credentials and request detailed certificates of analysis (COA).

How to Use This Compound in Your Projects

  1. Identify the Target Reaction: Determine if Netherland Diethyl(Phenylacetyl)Malonate fits your synthetic pathway.
  2. Source High-Quality Material: Purchase from trusted suppliers.
  3. Optimize Reaction Conditions: Adjust temperature, solvents, and catalysts based on literature and experimental data.
  4. Conduct Small-Scale Trials: Validate reactivity and yield.
  5. Scale Up Production: Once validated, proceed with larger batches following safety protocols.

Future Perspectives and Developments

As organic and pharmaceutical chemistry advances, the role of specialized intermediates like Netherland Diethyl(Phenylacetyl)Malonate is expected to grow. Innovations in green chemistry may lead to more sustainable synthesis routes, reducing environmental impact.

Research is ongoing into novel derivatives and applications, including potential uses in nanotechnology, drug delivery systems, and biodegradable materials.

Conclusion

Netherland Diethyl(Phenylacetyl)Malonate CAS 20320-59-6 is a pivotal chemical compound with broad applications across pharmaceuticals, organic synthesis, and agrochemicals. Its unique chemical structure allows it to serve as an essential intermediate in creating complex molecules vital to modern industry.

By understanding its synthesis, applications, safety considerations, and sourcing options, researchers and industry professionals can leverage this compound effectively and safely. Bio Base mineralized kerosene

References

  • Bmk Oil Center
  • Chemical databases and safety datasheets
  • Organic synthesis literature and research articles

Call to Action

If you're interested in sourcing Netherland Diethyl(Phenylacetyl)Malonate or seeking expert advice on its application, contact reputable chemical suppliers today. Stay ahead in your research and development projects by utilizing high-quality intermediates like CAS 20320-59-6.

Disclaimer: Always adhere to local regulations and safety guidelines when handling chemicals.

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